{"id":4065,"date":"2018-06-19T12:52:12","date_gmt":"2018-06-19T12:52:12","guid":{"rendered":"https:\/\/www.novonon.com\/blog\/2018\/06\/19\/grandmas-trauma-a-critical-appraisal-of-the-evidence-for-transgenerational-epigenetic-inheritance-in-humans\/"},"modified":"2018-06-19T12:52:12","modified_gmt":"2018-06-19T12:52:12","slug":"grandmas-trauma-a-critical-appraisal-of-the-evidence-for-transgenerational-epigenetic-inheritance-in-humans","status":"publish","type":"post","link":"https:\/\/www.novonon.com\/blog\/2018\/06\/19\/grandmas-trauma-a-critical-appraisal-of-the-evidence-for-transgenerational-epigenetic-inheritance-in-humans\/","title":{"rendered":"Grandma\u2019s trauma \u2013 a critical appraisal of the evidence for transgenerational epigenetic inheritance in humans"},"content":{"rendered":"
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Can molecular memories of our ancestors\u2019 experiences affect our own behaviour and physiology? That idea has certainly grabbed hold of the public imagination, under the banner of the seemingly ubiquitous buzzword \u201cepigenetics\u201d. <\/span>Transgenerational epigenetic inheritance<\/a> <\/span>is the idea that a person\u2019s experiences can somehow mark their genomes in ways that are passed on to their children and grandchildren. Those marks on the genome are then thought to influence gene expression and affect the behaviour and physiology of people who inherit them. <\/span><\/div>\n
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The way this notion is referred to \u2013 both in popular pieces and in the scientific literature \u2013 you\u2019d be forgiven for thinking it is an established fact in humans, based on mountains of consistent, compelling evidence. In fact, the opposite is true \u2013 it is based on the flimsiest of evidence from a very small number of studies with very small sample sizes and serious methodological flaws. [Note that there is, by contrast, very good evidence for this kind of mechanism in <\/span>nematodes<\/a> <\/span>and <\/span>plants<\/a> <\/span>and in specific circumstances involving transposable elements in <\/span>mice<\/a>].<\/span><\/div>\n
To save you the trouble, I dig into the dismal details below.<\/span><\/div>\n<\/blockquote>\n

http:\/\/www.wiringthebrain.com\/2018\/05\/grandmas-trauma-critical-appraisal-of.html?m=1<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Can molecular memories of our ancestors\u2019 experiences affect our own behaviour and physiology? That idea has certainly grabbed hold of the public imagination, under the banner of the seemingly ubiquitous buzzword \u201cepigenetics\u201d. Transgenerational epigenetic inheritance is the idea that a person\u2019s experiences can somehow mark their genomes in ways that are passed on to their […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-4065","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p3pfIY-13z","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts\/4065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/comments?post=4065"}],"version-history":[{"count":0,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts\/4065\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/media?parent=4065"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/categories?post=4065"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/tags?post=4065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}