{"id":935,"date":"2012-03-02T15:36:00","date_gmt":"2012-03-02T15:36:00","guid":{"rendered":"https:\/\/www.novonon.com\/blog\/2012\/03\/02\/breaking-good-how-to-synthesize-pseudoephedrine-sudafed-from-n-methylamphetamine-crystal-meth\/"},"modified":"2012-03-02T15:36:00","modified_gmt":"2012-03-02T15:36:00","slug":"breaking-good-how-to-synthesize-pseudoephedrine-sudafed-from-n-methylamphetamine-crystal-meth","status":"publish","type":"post","link":"https:\/\/www.novonon.com\/blog\/2012\/03\/02\/breaking-good-how-to-synthesize-pseudoephedrine-sudafed-from-n-methylamphetamine-crystal-meth\/","title":{"rendered":"Breaking Good: how to synthesize Pseudoephedrine (Sudafed) From N-Methylamphetamine (crystal meth)"},"content":{"rendered":"<div><\/div>\n<div>[Ha!! -Egg]<\/p>\n<h4>Sent to you via Google Reader<\/h4>\n<h2><a href=\"http:\/\/feedproxy.google.com\/~r\/boingboing\/iBag\/~3\/8P6KiXfKQQo\/scientific-paper-of-the-day-h.html\">Breaking Good: how to synthesize Pseudoephedrine (Sudafed) From N-Methylamphetamine (crystal meth)<\/a><\/h2>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/boingboing.net\/wp-content\/uploads\/2012\/02\/meth1.jpg?resize=600%2C400\" alt=\"\" title=\"meth1\" width=\"600\" height=\"400\"><\/p>\n<p>Genius scientific paper* of the day: &#8220;<a href=\"http:\/\/heterodoxy.cc\/meowdocs\/pseudo\/pseudosynth.pdf\" target=\"_blank\">A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine<\/a>, by O. Hai and I. B. Hakkenshit.&#8221; (PDF). <\/p>\n<p>A response by annoyed Sudafed users to the onerous demands by pharmacies for ID and tracking, due to the fact that this helpful and common over-the-counter drug can be used to manufacture crystal meth.<\/p>\n<p>Snip from the paper:<\/p>\n<p><\/p>\n<p><\/p>\n<blockquote>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/boingboing.net\/wp-content\/uploads\/2012\/02\/meth2.jpg?w=300\" alt=\"\" title=\"meth2\"  align=\"left\"><\/p>\n<p>A novel and straightforward synthesis of pseudoephidrine from<br \/>readily available N-methylamphetamine is presented.  This<br \/>practical synthesis is expected to be a disruptive technology<br \/>replacing the need to find an open pharmacy.<\/p>\n<p>Pseudoephedrine, active ingredient of Sudafed\u00ae, has long<br \/>been the most popular nasal decongestant in the United States<br \/>due to its effectiveness and relatively mild side effects [1].  In<br \/>recent years it has become increasingly difficult to obtain<br \/>psuedoephedine in many states because of its use as a<br \/>precursor for the illegal drug N-methylamphetamine (also<br \/>known under various names including crystal meth, meth, ice,<br \/>etc.)[1,2].  While in the past many stores were able to sell<br \/>pseudoephedrine, new laws in the United States have<br \/>restricted sales to pharmacies, with the medicine kept behind<br \/>the counter.  The pharmacies require signatures and<br \/>examination of government issued ID in order to purchase<br \/>pseudoephedrine.  Because the hours of availability of such<br \/>pharmacies are often limited, it would be of great interest to<br \/>have a simple synthesis of pseudoephedrine from reagents<br \/>which can be more readily procured.<\/p>\n<\/p>\n<\/p>\n<\/blockquote>\n<p><span><\/span><\/p>\n<blockquote><p>\n<br \/>A quick search of several neighborhoods of the United<br \/>States revealed that while pseudoephedrine is difficult to<br \/>obtain, N-methylamphetamine can be procured at almost any<br \/>time on short notice and in quantities sufficient for synthesis<br \/>of useful amounts of the desired material.  Moreover,<br \/>according to government maintained statistics, Nmethylmphetamine is becoming an increasingly attractive<br \/>starting material for pseudoephedrine, as the availability of Nmethylmphetamine has remained high while prices have<br \/>dropped and purity has increased [2].  We present here a<br \/>convenient series of transformations using reagents which can<br \/>be found in most well stocked organic chemistry laboratories<br \/>to produce psuedoephedrine from N-methylamphetamine. <\/p>\n<p><\/p>\n<\/blockquote>\n<p><\/p>\n<div align=\"center\">\n<br \/><a href=\"https:\/\/twitter.com\/#!\/yesthatkarim\/status\/174205217192153088\/photo\/1\" target=\"_blank\"><br \/><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/boingboing.net\/wp-content\/uploads\/2012\/02\/AmrmuNkCEAEF87x.jpg?resize=401%2C242\" alt=\"\" title=\"AmrmuNkCEAEF87x\" width=\"401\" height=\"242\"><\/a>\n<\/div>\n<p><...<\/div>\n","protected":false},"excerpt":{"rendered":"<p>[Ha!! -Egg] Sent to you via Google Reader Breaking Good: how to synthesize Pseudoephedrine (Sudafed) From N-Methylamphetamine (crystal meth) Genius scientific paper* of the day: &#8220;A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine, by O. Hai and I. B. Hakkenshit.&#8221; (PDF). A response by annoyed Sudafed users to the onerous demands by pharmacies for [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-935","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p3pfIY-f5","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts\/935","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/comments?post=935"}],"version-history":[{"count":0,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/posts\/935\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/media?parent=935"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/categories?post=935"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.novonon.com\/blog\/wp-json\/wp\/v2\/tags?post=935"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}